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Architecture of P2Y Nucleotide Receptors: Structural Comparison Based on Sequence Analysis, Mutagenesis, and Homology Modeling()

Human P2Y receptors encompass at least eight subtypes of Class A G protein-coupled receptors (GPCRs), responding to adenine and/or uracil nucleotides. Using a BLAST search against the Homo sapiens subset of the SWISS–PROT and TrEMBL databases, we identified 68 proteins showing high similarity to P2Y...

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Bibliografiska uppgifter
Huvudupphovsmän: Costanzi, Stefano, Mamedova, Liaman, Gao, Zhan-Guo, Jacobson, Kenneth A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431558/
https://ncbi.nlm.nih.gov/pubmed/15481977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm049914c
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