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Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y(6) nucleotide receptors

The physiological role of the P2Y(6) nucleotide receptor may involve cardiovascular, immune and digestive functions based on the receptor tissue distribution, and selective antagonists for this receptor are lacking. We have synthesized a series of symmetric aryl diisothiocyanate derivatives and exam...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mamedova, Liaman K., Joshi, Bhalchandra V., Gao, Zhan-Guo, von Kügelgen, Ivar, Jacobson, Kenneth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413726/
https://ncbi.nlm.nih.gov/pubmed/15081875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2004.01.011
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