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Evidence for the Recognition of Non-Nucleotide Antagonists Within the Transmembrane Domains of the Human P2Y(1) Receptor

Site-directed mutagenesis was used to search for amino acid residues of the human P2Y(1) receptor involved in the binding of the P2 receptor antagonists pyridoxal-5′-phosphate-6-azophenyl-2,4-disulfonate (PPADS), its analogue 6-(2′-chloro-phenylazo)-pyridoxal-α(5)-phosphate (MRS 2210), the suramin a...

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Detalhes bibliográficos
Main Authors: Guo, Danping, von Kügelgen, Ivar, Moro, Stefano, Kim, Yong-Chul, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479677/
https://ncbi.nlm.nih.gov/pubmed/23105165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.10145
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