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Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways
Toll-like receptor 4 (TLR4) and TLR2 were shown to be activated by saturated fatty acids (SFAs) but inhibited by docosahexaenoic acid (DHA). However, one report suggested that SFA-induced TLR activation in cell culture systems is due to contaminants in BSA used for solubilizing fatty acids. This rep...
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Główni autorzy: | , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
The American Society for Biochemistry and Molecular Biology
2012
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413240/ https://ncbi.nlm.nih.gov/pubmed/22766885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D029546 |
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