Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways

Toll-like receptor 4 (TLR4) and TLR2 were shown to be activated by saturated fatty acids (SFAs) but inhibited by docosahexaenoic acid (DHA). However, one report suggested that SFA-induced TLR activation in cell culture systems is due to contaminants in BSA used for solubilizing fatty acids. This rep...

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Main Authors: Huang, Shurong, Rutkowsky, Jennifer M., Snodgrass, Ryan G., Ono-Moore, Kikumi D., Schneider, Dina A., Newman, John W., Adams, Sean H., Hwang, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413240/
https://ncbi.nlm.nih.gov/pubmed/22766885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D029546
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