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Acylcarnitines activate proinflammatory signaling pathways
Incomplete β-oxidation of fatty acids in mitochondria is a feature of insulin resistance and type 2 diabetes mellitus (T2DM). Previous studies revealed that plasma concentrations of medium- and long-chain acylcarnitines (by-products of incomplete β-oxidation) are elevated in T2DM and insulin resista...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059985/ https://ncbi.nlm.nih.gov/pubmed/24760988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00656.2013 |
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