Acylcarnitines activate proinflammatory signaling pathways

Incomplete β-oxidation of fatty acids in mitochondria is a feature of insulin resistance and type 2 diabetes mellitus (T2DM). Previous studies revealed that plasma concentrations of medium- and long-chain acylcarnitines (by-products of incomplete β-oxidation) are elevated in T2DM and insulin resista...

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Autors principals: Rutkowsky, Jennifer M., Knotts, Trina A., Ono-Moore, Kikumi D., McCoin, Colin S., Huang, Shurong, Schneider, Dina, Singh, Shamsher, Adams, Sean H., Hwang, Daniel H.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059985/
https://ncbi.nlm.nih.gov/pubmed/24760988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00656.2013
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