Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; Modulation by dietary fatty acids

Many studies have shown that TLR4 and TLR2 deficient mice are protected from high fat diet-induced inflammation and insulin resistance, suggesting that saturated fatty acids derived from the high fat diet activate TLR-mediated proinflammatory signaling pathways and induce insulin resistance. However...

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Hlavní autoři: Snodgrass, Ryan G., Huang, Shurong, Choi, Il-Whan, Rutledge, John C., Hwang, Daniel H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825708/
https://ncbi.nlm.nih.gov/pubmed/24043885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300298
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