The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages

Atherosclerosis is considered a chronic inflammatory disease in which monocytes and macrophages are critical. These cells express CD14, toll-like receptor (TLR) 2, and TLR4 on their surfaces, are activated by minimally modified low-density lipoprotein (mmLDL) and are capable of secreting pro-inflamm...

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Bibliografiske detaljer
Main Authors: Chávez-Sánchez, Luis, Chávez-Rueda, Karina, Legorreta-Haquet, Maria Victoria, Zenteno, Edgar, Ledesma-Soto, Yadira, Montoya-Díaz, Eduardo, Tesoro-Cruz, Emiliano, Madrid-Miller, Alejandra, Blanco-Favela, Francisco
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964726/
https://ncbi.nlm.nih.gov/pubmed/20946675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-117
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