Differential inflammasome expression and IL-1β secretion in monocyte-derived dendritic cells differentiated with IL-4 or IFN-α

BACKGROUND: NLRP3-inflammasome activation was evaluated in monocyte-derived dendritic cells (DC) obtained through IL-4 (IL4-DC) or IFN-α (IFN-DC) protocols and pulsed with chemically inactivated HIV-1. Inflammasome’ genes expression and IL-1β secretion were compared in DC isolated from 15 healthy su...

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Bibliographic Details
Main Authors: Pontillo, Alessandra, Santillo, Bruna T, Duarte, Alberto JS, Oshiro, Telma M
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892092/
https://ncbi.nlm.nih.gov/pubmed/24373498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-10-35
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