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HBsAg Inhibits IFN-α Production in Plasmacytoid Dendritic Cells through TNF-α and IL-10 Induction in Monocytes

Type I Interferon (IFN) is one of the first lines of defense against viral infection. Plasmacytoid dendritic cells (pDCs) are professional IFN-α-producing cells that play an important role in the antiviral immune response. Previous studies have reported that IFN-α production is impaired in chronic h...

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Detalhes bibliográficos
Main Authors: Shi, Bisheng, Ren, Guangxu, Hu, Yunwen, Wang, Sen, Zhang, Zhanqing, Yuan, Zhenghong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443230/
https://ncbi.nlm.nih.gov/pubmed/23024774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044900
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