Transgenic mice with ectopic expression of constitutively active TLR4 in adipose tissues do not show impaired insulin sensitivity

INTRODUCTION: Chronic low‐grade inflammation is associated with obesity and diabetes. However, what causes and mediates chronic inflammation in metabolic disorders is not well understood. Toll‐like receptor 4 (TLR4) mediates both infection‐induced and sterile inflammation by recognizing pathogen‐ass...

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Bibliografiske detaljer
Udgivet i:Immun Inflamm Dis
Main Authors: Ono‐Moore, Kikumi D., Zhao, Ling, Huang, Shurong, Kim, Jeonga, Rutkowsky, Jennifer M., Snodgrass, Ryan G., Schneider, Dina A., Quon, Michael J., Graham, James L., Havel, Peter J., Hwang, Daniel H.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691308/
https://ncbi.nlm.nih.gov/pubmed/28776958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.162
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