KH domains with impaired nucleic acid binding as a tool for functional analysis

In eukaryotes, RNA-binding proteins that contain multiple K homology (KH) domains play a key role in coordinating the different steps of RNA synthesis, metabolism and localization. Understanding how the different KH modules participate in the recognition of the RNA targets is necessary to dissect th...

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Detalles Bibliográficos
Autores principales: Hollingworth, David, Candel, Adela M., Nicastro, Giuseppe, Martin, Stephen R., Briata, Paola, Gherzi, Roberto, Ramos, Andres
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413153/
https://ncbi.nlm.nih.gov/pubmed/22547390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks368
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