PHOSPHORYLATION-MEDIATED UNFOLDING OF A KH DOMAIN REGULATES KSRP LOCALISATION VIA 14-3-3 BINDING

The AU-rich-element (ARE)–mediated mRNA degradation activity of the RNA-binding K-homology Splicing Regulator Protein (KSRP) is regulated by phosphorylation of a serine within its N-terminal KH domain (KH1). In the cell phosphorylation promotes the interaction between KSRP and 14-3-3ζ protein and im...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Díaz-Moreno, Irene, Hollingworth, David, Frenkiel, Thomas A., Kelly, Geoff, Martin, Stephen, Howell, Steven, García-Mayoral, MaríaFlor, Gherzi, Roberto, Briata, Paola, Ramos, Andres
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858377/
https://ncbi.nlm.nih.gov/pubmed/19198587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1558
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados