Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

KSRP is a multi-domain RNA-binding protein that recruits the exosome-containing mRNA degradation complex to mRNAs coding for cellular proliferation and inflammatory response factors. The selectivity of this mRNA degradation mechanism relies on KSRP recognition of AU-rich elements in the mRNA 3′UTR,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Díaz-Moreno, Irene, Hollingworth, David, Kelly, Geoff, Martin, Stephen, García-Mayoral, MaríaFlor, Briata, Paola, Gherzi, Roberto, Ramos, Andres
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926597/
https://ncbi.nlm.nih.gov/pubmed/20385598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq216
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker