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The RNA-binding Protein KSRP Promotes the Biogenesis of a Subset of miRNAs

Consistent with the role of microRNAs (miRNAs) in down-regulating gene expression by reducing translation and/or stability of target mRNAs1, the levels of specific miRNAs are important for correct embryonic development and have been linked to several forms of cancer2-4. However, the regulatory mecha...

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Detalhes bibliográficos
Main Authors: Trabucchi, Michele, Briata, Paola, Garcia-Mayoral, MariaFlor, Haase, Astrid D., Filipowicz, Witold, Ramos, Andres, Gherzi, Roberto, Rosenfeld, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768332/
https://ncbi.nlm.nih.gov/pubmed/19458619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08025
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