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KH domains with impaired nucleic acid binding as a tool for functional analysis

In eukaryotes, RNA-binding proteins that contain multiple K homology (KH) domains play a key role in coordinating the different steps of RNA synthesis, metabolism and localization. Understanding how the different KH modules participate in the recognition of the RNA targets is necessary to dissect th...

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Detalhes bibliográficos
Main Authors: Hollingworth, David, Candel, Adela M., Nicastro, Giuseppe, Martin, Stephen R., Briata, Paola, Gherzi, Roberto, Ramos, Andres
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413153/
https://ncbi.nlm.nih.gov/pubmed/22547390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks368
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