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The role of a clinically important mutation in the fold and RNA-binding properties of KH motifs
We have investigated the role in the fold and RNA-binding properties of the KH modules of a hydrophobic to asparagine mutation of clinical importance in the fragile X syndrome. The mutation involves a well-conserved hydrophobic residue close to the N terminus of the second helix of the KH fold (α2(3...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Copyright 2003 by RNA Society
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370396/ https://ncbi.nlm.nih.gov/pubmed/12592003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2168503 |
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