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Role of the irreplaceable residues in the LacY alternating access mechanism

Few side chains in the galactoside/H(+) symporter LacY (lactose permease of Escherichia coli) are irreplaceable for an alternating access mechanism in which sugar binding induces closing of the cytoplasmic cavity and reciprocal opening of a periplasmic cavity. In this study, each irreplaceable resid...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhou, Yonggang, Jiang, Xiaoxu, Kaback, H. Ronald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412042/
https://ncbi.nlm.nih.gov/pubmed/22802658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210684109
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