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Probing of the rates of alternating access in LacY with Trp fluorescence
Sugar/H(+) symport by lactose permease (LacY) utilizes an alternating access mechanism in which sugar and H(+) binding sites in the middle of the molecule are alternatively exposed to either side of the membrane by sequential opening and closing of inward- and outward-facing hydrophilic cavities. He...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799877/ https://ncbi.nlm.nih.gov/pubmed/19959662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911434106 |
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