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Role of the irreplaceable residues in the LacY alternating access mechanism
Few side chains in the galactoside/H(+) symporter LacY (lactose permease of Escherichia coli) are irreplaceable for an alternating access mechanism in which sugar binding induces closing of the cytoplasmic cavity and reciprocal opening of a periplasmic cavity. In this study, each irreplaceable resid...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412042/ https://ncbi.nlm.nih.gov/pubmed/22802658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210684109 |
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