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Speed, dissipation, and error in kinetic proofreading

Proofreading mechanisms increase specificity in biochemical reactions by allowing for the dissociation of intermediate complexes. These mechanisms disrupt and reset the reaction to undo errors at the cost of increased time of reaction and free energy expenditure. Here, we draw an analogy between pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Murugan, Arvind, Huse, David A., Leibler, Stanislas
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409783/
https://ncbi.nlm.nih.gov/pubmed/22786930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119911109
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