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Speed, dissipation, and error in kinetic proofreading

Proofreading mechanisms increase specificity in biochemical reactions by allowing for the dissociation of intermediate complexes. These mechanisms disrupt and reset the reaction to undo errors at the cost of increased time of reaction and free energy expenditure. Here, we draw an analogy between pro...

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Détails bibliographiques
Auteurs principaux: Murugan, Arvind, Huse, David A., Leibler, Stanislas
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409783/
https://ncbi.nlm.nih.gov/pubmed/22786930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119911109
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