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Speed, dissipation, and error in kinetic proofreading

Proofreading mechanisms increase specificity in biochemical reactions by allowing for the dissociation of intermediate complexes. These mechanisms disrupt and reset the reaction to undo errors at the cost of increased time of reaction and free energy expenditure. Here, we draw an analogy between pro...

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Detalhes bibliográficos
Main Authors: Murugan, Arvind, Huse, David A., Leibler, Stanislas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409783/
https://ncbi.nlm.nih.gov/pubmed/22786930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119911109
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