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Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading

In the context of cell signaling, kinetic proofreading was introduced to explain how cells can discriminate among ligands based on a kinetic parameter, the ligand-receptor dissociation rate constant. In the kinetic proofreading model of cell signaling, responses occur only when a bound receptor unde...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Hlavacek, William S., Redondo, Antonio, Metzger, Henry, Wofsy, Carla, Goldstein, Byron
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 2001
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34662/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121172298
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