Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading

In the context of cell signaling, kinetic proofreading was introduced to explain how cells can discriminate among ligands based on a kinetic parameter, the ligand-receptor dissociation rate constant. In the kinetic proofreading model of cell signaling, responses occur only when a bound receptor unde...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hlavacek, William S., Redondo, Antonio, Metzger, Henry, Wofsy, Carla, Goldstein, Byron
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390967/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121172298
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