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Paraoxonase 2 decreases renal reactive oxygen species production, lowers blood pressure, and mediates dopamine D(2) receptor-induced inhibition of NADPH oxidase
The dopamine D(2) receptor (D(2)R) regulates renal reactive oxygen species (ROS) production and impaired D(2)R function results in ROS-dependent hypertension. Paraoxonase 2 (PON2), which belongs to the paraoxonase gene family, is expressed in various tissues, acting to protect against cellular oxida...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408834/ https://ncbi.nlm.nih.gov/pubmed/22634053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.05.015 |
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