Role of renal DJ-1 in the Pathogenesis of Hypertension Associated with Increased ROS Production

The D(2) dopamine receptor (D(2)R) is important in the pathogenesis of essential hypertension. We have already reported that systemic deletion of the D(2)R gene in mice results in reactive oxygen species (ROS)-dependent hypertension, suggesting that the D(2)R has antioxidant effect. However, the mec...

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Main Authors: Cuevas, Santiago, Zhang, Yanrong, Yang, Yu, Escano, Crisanto, Asico, Laureano, Jones, John E., Armando, Ines, Jose, Pedro A.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395064/
https://ncbi.nlm.nih.gov/pubmed/22215708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.185744
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