Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D(2) receptor-induced inhibition of ROS production

The D(2) dopamine receptor (D(2)R) decreases renal reactive oxygen species (ROS) production and regulates blood pressure, in part, via positive regulation of paraoxonase 2 (PON2). Sestrin2, a highly conserved antioxidant protein, regulates intracellular ROS level by regenerating hyper-oxidized perox...

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Main Authors: Yang, Yu, Cuevas, Santiago, Yang, Sufei, Villar, Van Anthony, Escano, Crisanto, Asico, Laureano, Yu, Peiying, Jiang, Xiaoliang, Weinman, Edward J., Armando, Ines, Jose, Pedro A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162832/
https://ncbi.nlm.nih.gov/pubmed/25024286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03840
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