Deficient Dopamine D(2) Receptor Function Causes Renal Inflammation Independently of High Blood Pressure

Renal dopamine receptors participate in the regulation of blood pressure. Genetic factors, including polymorphisms of the dopamine D(2) receptor gene (DRD2) are associated with essential hypertension, but the mechanisms of their contribution are incompletely understood. Mice lacking Drd2 (D(2)−/−) h...

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Bibliographic Details
Main Authors: Zhang, Yanrong, Cuevas, Santiago, Asico, Laureano D., Escano, Crisanto, Yang, Yu, Pascua, Annabelle M., Wang, Xiaoyan, Jones, John E., Grandy, David, Eisner, Gilbert, Jose, Pedro A., Armando, Ines
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375266/
https://ncbi.nlm.nih.gov/pubmed/22719934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038745
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