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Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D(2) receptor-induced inhibition of ROS production
The D(2) dopamine receptor (D(2)R) decreases renal reactive oxygen species (ROS) production and regulates blood pressure, in part, via positive regulation of paraoxonase 2 (PON2). Sestrin2, a highly conserved antioxidant protein, regulates intracellular ROS level by regenerating hyper-oxidized perox...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162832/ https://ncbi.nlm.nih.gov/pubmed/25024286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03840 |
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