D(5) dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1

D(5) dopamine receptor (D(5)R) knock-out mice (D(5)(−/−)) have a higher blood pressure (BP) and higher reactive oxygen species (ROS) production than their D(5)R wild-type littermates (D(5)(+/+)). We tested the hypothesis that the high BP and increased ROS production in D(5)(−/−) mice may be caused b...

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Main Authors: Lu, Quansheng, Yang, Yu, Villar, Van Anthony, Asico, Laureano, Jones, John E, Yu, Peiying, Li, Hewang, Weinman, Edward J, Eisne, Gilbert M, Jose, Pedro A
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061571/
https://ncbi.nlm.nih.gov/pubmed/23425954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2013.9
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