Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation

The dopamine D(3) receptor (D(3)R) is crucial in the regulation of blood pressure and sodium balance, in that Drd3 gene ablation in mice results in hypertension and failure to excrete a dietary salt load. The mechanism responsible for the renal sodium retention in these mice is largely unknown. We n...

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Main Authors: Armando, Ines, Villar, Van Anthony M., Jones, John E., Lee, Hewang, Wang, Xiaoyan, Asico, Laureano D., Yu, Peiying, Yang, Jian, Escano, Crisanto S., Pascua-Crusan, Annabelle M., Felder, Robin A., Jose, Pedro A.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2014
主題:
Research Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929671/
https://ncbi.nlm.nih.gov/pubmed/24308971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-243840
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