Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation

The dopamine D(3) receptor (D(3)R) is crucial in the regulation of blood pressure and sodium balance, in that Drd3 gene ablation in mice results in hypertension and failure to excrete a dietary salt load. The mechanism responsible for the renal sodium retention in these mice is largely unknown. We n...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Armando, Ines, Villar, Van Anthony M., Jones, John E., Lee, Hewang, Wang, Xiaoyan, Asico, Laureano D., Yu, Peiying, Yang, Jian, Escano, Crisanto S., Pascua-Crusan, Annabelle M., Felder, Robin A., Jose, Pedro A.
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2014
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929671/
https://ncbi.nlm.nih.gov/pubmed/24308971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-243840
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