Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells

Hypertension is a multigenic disorder in which abnormal counterregulation between dopamine and Ang II plays a role. Recent studies suggest that this counterregulation results, at least in part, from regulation of the expression of both the antihypertensive dopamine 5 receptor (D(5)R) and the prohype...

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Autores principales: Li, Hewang, Armando, Ines, Yu, Peiying, Escano, Crisanto, Mueller, Susette C., Asico, Laureano, Pascua, Annabelle, Lu, Quansheng, Wang, Xiaoyan, Villar, Van Anthony M., Jones, John E., Wang, Zheng, Periasamy, Ammasi, Lau, Yuen-Sum, Soares-da-Silva, Patricio, Creswell, Karen, Guillemette, Gaétan, Sibley, David R., Eisner, Gilbert, Felder, Robin A., Jose, Pedro A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373421/
https://ncbi.nlm.nih.gov/pubmed/18464932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33637
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