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Functional single-cell hybridoma screening using droplet-based microfluidics
Monoclonal antibodies can specifically bind or even inhibit drug targets and have hence become the fastest growing class of human therapeutics. Although they can be screened for binding affinities at very high throughput using systems such as phage display, screening for functional properties (e.g.,...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406880/ https://ncbi.nlm.nih.gov/pubmed/22753519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204514109 |
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