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Functional TCR T cell screening using single-cell droplet microfluidics

Adoptive T cell transfer, in particular TCR T cell therapy, holds great promise for cancer immunotherapy with encouraging clinical results. However, finding the right TCR T cell clone is a tedious, time-consuming, and costly process. Thus, there is a critical need for single cell technologies to con...

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Bibliografski detalji
Izdano u:Lab Chip
Glavni autori: Segaliny, Aude I., Li, Guideng, Kong, Lingshun, Ren, Ci, Chen, Xiaoming, Wang, Jessica K., Baltimore, David, Wu, Guikai, Zhao, Weian
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279597/
https://ncbi.nlm.nih.gov/pubmed/30397689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8lc00818c
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