Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity

Ultrahigh-throughput screening (uHTS) techniques can identify unique functionality from millions of variants. To mimic the natural selection mechanisms that occur by compartmentalization in vivo, we developed a technique based on single-cell encapsulation in droplets of a monodisperse microfluidic d...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Terekhov, Stanislav S., Smirnov, Ivan V., Stepanova, Anastasiya V., Bobik, Tatyana V., Mokrushina, Yuliana A., Ponomarenko, Natalia A., Belogurov, Alexey A., Rubtsova, Maria P., Kartseva, Olga V., Gomzikova, Marina O., Moskovtsev, Alexey A., Bukatin, Anton S., Dubina, Michael V., Kostryukova, Elena S., Babenko, Vladislav V., Vakhitova, Maria T., Manolov, Alexander I., Malakhova, Maja V., Kornienko, Maria A., Tyakht, Alexander V., Vanyushkina, Anna A., Ilina, Elena N., Masson, Patrick, Gabibov, Alexander G., Altman, Sidney
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347554/
https://ncbi.nlm.nih.gov/pubmed/28202731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621226114
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