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Droplet microfluidic technology for single-cell high-throughput screening

We present a droplet-based microfluidic technology that enables high-throughput screening of single mammalian cells. This integrated platform allows for the encapsulation of single cells and reagents in independent aqueous microdroplets (1 pL to 10 nL volumes) dispersed in an immiscible carrier oil...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brouzes, Eric, Medkova, Martina, Savenelli, Neal, Marran, Dave, Twardowski, Mariusz, Hutchison, J. Brian, Rothberg, Jonathan M., Link, Darren R., Perrimon, Norbert, Samuels, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732882/
https://ncbi.nlm.nih.gov/pubmed/19617544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903542106
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