Droplet microfluidic technology for single-cell high-throughput screening

We present a droplet-based microfluidic technology that enables high-throughput screening of single mammalian cells. This integrated platform allows for the encapsulation of single cells and reagents in independent aqueous microdroplets (1 pL to 10 nL volumes) dispersed in an immiscible carrier oil...

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Main Authors: Brouzes, Eric, Medkova, Martina, Savenelli, Neal, Marran, Dave, Twardowski, Mariusz, Hutchison, J. Brian, Rothberg, Jonathan M., Link, Darren R., Perrimon, Norbert, Samuels, Michael L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Physical Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732882/
https://ncbi.nlm.nih.gov/pubmed/19617544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903542106
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