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Functional single-cell hybridoma screening using droplet-based microfluidics

Monoclonal antibodies can specifically bind or even inhibit drug targets and have hence become the fastest growing class of human therapeutics. Although they can be screened for binding affinities at very high throughput using systems such as phage display, screening for functional properties (e.g.,...

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Detaylı Bibliyografya
Asıl Yazarlar: Debs, Bachir El, Utharala, Ramesh, Balyasnikova, Irina V., Griffiths, Andrew D., Merten, Christoph A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406880/
https://ncbi.nlm.nih.gov/pubmed/22753519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204514109
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