Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice.

Normal and mutant human alpha-1-antitrypsin genes were cloned from a PiMZ heterozygous individual. Nucleotide sequence comparison demonstrated a T to C transition in exon III and an G to A transition in exon V of the PiZ gene. A 14.4 kb DNA fragment containing the entire PiM gene plus 2 kb of 5' and...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Sifers, R N, Carlson, J A, Clift, S M, DeMayo, F J, Bullock, D W, Woo, S L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1987
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340561/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.4.1459
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