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Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice.

Normal and mutant human alpha-1-antitrypsin genes were cloned from a PiMZ heterozygous individual. Nucleotide sequence comparison demonstrated a T to C transition in exon III and an G to A transition in exon V of the PiZ gene. A 14.4 kb DNA fragment containing the entire PiM gene plus 2 kb of 5' and...

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Publicado en:Nucleic Acids Res
Autores principales: Sifers, R N, Carlson, J A, Clift, S M, DeMayo, F J, Bullock, D W, Woo, S L
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1987
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.4.1459
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