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Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice.

Normal and mutant human alpha-1-antitrypsin genes were cloned from a PiMZ heterozygous individual. Nucleotide sequence comparison demonstrated a T to C transition in exon III and an G to A transition in exon V of the PiZ gene. A 14.4 kb DNA fragment containing the entire PiM gene plus 2 kb of 5'...

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Hlavní autoři: Sifers, R N, Carlson, J A, Clift, S M, DeMayo, F J, Bullock, D W, Woo, S L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC340561/
https://ncbi.nlm.nih.gov/pubmed/3029716
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