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Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice.
Normal and mutant human alpha-1-antitrypsin genes were cloned from a PiMZ heterozygous individual. Nucleotide sequence comparison demonstrated a T to C transition in exon III and an G to A transition in exon V of the PiZ gene. A 14.4 kb DNA fragment containing the entire PiM gene plus 2 kb of 5'...
Bewaard in:
| Hoofdauteurs: | , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1987
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC340561/ https://ncbi.nlm.nih.gov/pubmed/3029716 |
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