Á lódáil...
Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice.
Circulating alpha 1-antitrypsin is synthesized primarily in the liver and secreted into the bloodstream, where it serves as the major protease inhibitor. The PiZ variant of alpha 1-antitrypsin is associated with decreased levels of the protein in sera as a result of its retention within hepatocytes....
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Main Authors: | , , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
1989
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC303805/ https://ncbi.nlm.nih.gov/pubmed/2784798 |
Clibeanna: |
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