The human alpha-1-antitrypsin gene is efficiently expressed from two tissue-specific promotors in transgenic mice.
Alpha 1-antitrypsin (alpha 1AT) present in large amounts in human serum and synthesized predominantly in hepatocytes, is the most abundant protease inhibitor and alpha 1AT mutant proteins are associated with hereditary disorders. To investigate the regulation of the normal human alpha 1AT gene, we h...
保存先:
| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
1987
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| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3498933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.18.7519 |
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