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Cells and Cell Lysates: A Direct Approach for Engineering Antibodies Against Membrane Proteins Using Yeast Surface Display

Membrane proteins (MPs) are often desirable targets for antibody engineering. However, the majority of antibody engineering platforms depend implicitly on aqueous solubility of the target antigen which is, at best, problematic for MPs. Recombinant, soluble forms of MPs have been successfully employe...

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Autores principales: Tillotson, Benjamin J., Cho, Yong Ku, Shusta, Eric V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405166/
https://ncbi.nlm.nih.gov/pubmed/22449570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.03.010
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