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Cells and Cell Lysates: A Direct Approach for Engineering Antibodies Against Membrane Proteins Using Yeast Surface Display

Membrane proteins (MPs) are often desirable targets for antibody engineering. However, the majority of antibody engineering platforms depend implicitly on aqueous solubility of the target antigen which is, at best, problematic for MPs. Recombinant, soluble forms of MPs have been successfully employe...

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Autori principali: Tillotson, Benjamin J., Cho, Yong Ku, Shusta, Eric V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405166/
https://ncbi.nlm.nih.gov/pubmed/22449570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.03.010
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