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Cells and Cell Lysates: A Direct Approach for Engineering Antibodies Against Membrane Proteins Using Yeast Surface Display

Membrane proteins (MPs) are often desirable targets for antibody engineering. However, the majority of antibody engineering platforms depend implicitly on aqueous solubility of the target antigen which is, at best, problematic for MPs. Recombinant, soluble forms of MPs have been successfully employe...

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Detalhes bibliográficos
Main Authors: Tillotson, Benjamin J., Cho, Yong Ku, Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405166/
https://ncbi.nlm.nih.gov/pubmed/22449570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.03.010
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