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Antibody library screens using detergent-solubilized mammalian cell lysates as antigen sources

High-throughput generation of antibodies against cellular components is currently a challenge in proteomics, therapeutic development and other biological applications. It is particularly challenging to raise antibodies that target membrane proteins due to their insolubility in aqueous solutions. To...

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Detalhes bibliográficos
Main Authors: Cho, Yong Ku, Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920304/
https://ncbi.nlm.nih.gov/pubmed/20498037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq029
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